Rewriting Human Aging with Physics and AI.

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Gero is a therapeutics company targeting the root physics of aging to add decades — not just years — of healthy life.

Our mission is to intercept functional decline before it manifests as disease, restoring resilience and doubling healthy human lifespan within a single generation.

FOUNDATIONAL SCIENCE

Our mission is to develop drugs that restore resilience, delay disease, and double healthy human lifespan within a single generation.

Foundational Models
of Human Health

Our AI is trained on real-world datasets (100M+ patient records), mapping aging trajectories across populations to reveal causal pathways — not just correlations — driving diseases and aging itself.

Physics-Informed,
Interpretable AI Models

Grounded in thermodynamics, our models separate irreversible aging from reversible disease processes, pinpointing targets that restore systemic resilience and control the rate of aging and disease progression.

Balanced Business Model

We collaborate with pharma on high‑value, age‑related indications while advancing scientifically solid anti‑aging interventions in‑house — de‑risking the science and accelerating patient impact.

ABOUT GERO

Building at the crossroads of theoretical physics, cutting-edge biology, and generative AI.

Our platform is trained on more than 100M+ longitudinal medical records — one of the world’s deepest views into how human bodies age and recover in real life. Using physics-informed models, we translate this data into a quantitative picture of aging being driven by entropy buildup leading to system-wide loss of resilience that makes each stressor a little harder to shake off.

Knowledge is power. We aim at an ambitious yet achievable goal: to deliver first-in class therapeutics able to double human health and lifespan within a single generation.

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Press Release

July 7, 2025

Chugai and Gero Enter into Joint Research and License Agreement to Develop Novel Therapies for Age-Related Diseases

WHY NOW

We live in an unprecedented time:

Longitudinal clinical data at scale and deep molecular datasets

Advances in machine learning and generative modelling

A new understanding of aging as a thermodynamic process

Together, these shifts enable a fundamentally new way to design medicines that intervene earlier, act deeper, and last longer.

MILESTONES AND MOMENTUM

The convergence of physics, biology, and AI unlocking a new era in drug discovery.

MISSION

To eliminate root causes of age-related diseases and double human health- and lifespan within the current generation

Work regardless of patient age

Target only reversible conditions

Effects within clinical trial-time frames

WHY NOW

We are living at the best of times longitudinal data + machine learning = physics-informed modelling of human biology

2025

ProtoBind-Diff launched: First AI model for structure-free drug design using only protein sequence

2023

Research collaboration with Pfizer to discover targets for fibrotic disease

2025

ProtoBind-Diff launched: First AI model for structure-free drug design using only protein sequence

Unsupervised learning of aging principles from longitudinal data

2025

$250M partnership with Chugai Pharmaceutical to co-develop novel antibody drugs for aging

Longitudinal analysis

2023

Research collaboration with Pfizer to discover targets for fibrotic disease

2019 - 2021

Landmark publications defining resilience and biological age, the first identification of human maximum lifespan from biomedical data

Gero Real World Data Set is built

OUR SCIENCE

Understanding Aging as a Systems Failure and Engineering Drugs to Fix It

At Gero, we’re not treating symptoms. We’re targeting the underlying physics of aging itself.

Aging is not a law of nature, it’s a universal property of complex dynamic systems, which can be modelled, measured, and modified.

Drawing from physics, biology, and real-world human data, Gero has developed a first-principles understanding of aging that separates irreversible decline from reversible disease processes.

This insight powers our discovery of therapeutic targets and fuels the design of medicines that restore resilience, intercept functional decline, and extend human healthspan.

A New Framework for Aging Biology

For decades, aging research has focused on the so-called Hallmarks of Aging—accumulated damage and cellular deterioration. But these models haven’t produced disease-modifying therapies or meaningful lifespan extension.

Our findings

Gero’s work shows that aging is fundamentally a loss of systemic resilience driven by increasing entropy.

Theory of Aging

Our physics-informed theory of aging generalizes the earlier hallmarks of aging and damage accumulation theories and provides higher level regulators of aging in long lived mammals, including pets and humans.

A roadmap to better therapies

The framework provides a roadmap to therapies that may produce a lot better life extension effects, is published this framework in top-tier.